AbNano™ VHH Discovery Services
Conventional antibodies are one of the most widely used research tools in the biopharma industry. Yet despite their popularity, limitations in targeted therapeutics exist – due to both their structure and size, prohibiting their ability to stably reach target epitopes.
VHH antibodies can help overcome these challenges and are quickly becoming a promising tool in targeted therapeutic discovery and development.
Our vertically integrated single-domain antibody discovery process begins with immunization of llamas and alpacas. Proprietary methods are used to ensure the VHH region is amplified and cloned into the phagemid for phage display panning and screening for VHH hits, resulting in complete sequences of your custom VHH library or recombinant expression of the single-domain antibody.
We offer complete control over timeline and discovery
- Completely in-house discovery process
- Immune libraries generate superior binders to the desired target
- Flexible immunization schedule and real-time serum titer monitoring
- Panning isolates binders with preferred selectivity, affinity, and other characteristics
FAQs
What kind of immunogens can you work with?
How long will it take to get my unique VHH sequence?
Can you engineer VHH for diagnostic or therapeutic applications?
