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PathPlex® IHC Panels

PathPlex® IHC Panels are preformatted and optimized to work together, saving you time and money and leading to stronger signals. Each antibody has been validated for IHC and utilized in a multiplex format by our own scientists using Opal™ Tyramide Signal Amplification (TSA). Quickly detect multiple antigens in a single tissue section to gain a clear understanding of the tumor microenvironment without compromising samples with Bethyl PathPlex® IHC Panels.

Multiplex immunohistochemistry allows the researcher to visualize multiple biomarker proteins on a single tissue sample. The application of multiplex immunohistochemistry not only allows the researcher to identify which cells contain the biomarkers of interest but also details the spatial arrangements of cells allowing a deeper understanding of the underlying biology. The applications of multiplex immunohistochemistry are numerous and span clinical, translational, and basic research applications.

Core panels are listed below. Additional antibodies can be purchased to add into these panels, depending on your research needs.

Multicolor immunohistochemistry (mIHC) staining with PathPlex® Multiplex Antibodies
  • NEW!
    Immune Checkpoint PathPlex® Panel (CD3E, CD8 alpha, PD-L1)

    Bethyl Laboratories Catalog # A810-001

    bethyl
    Validated Documents (3)

    Target: CD3E CD8 alpha PD-L1

    Reactivity: Human

    Platforms: PhenoImager™ HT

    Detection of human CD3E (orange), CD8 alpha (red), and PD-L1 (green) in FFPE breast carcinoma by IHC-IF. 1 Figure
    $1,043.00
  • NEW!
    Cell Proliferation and Metastasis PathPlex® Panel (CD3E, Granzyme B, CD8 alpha, Cytokeratin, Ki-67, SOX10)

    Bethyl Laboratories Catalog # A810-006

    bethyl
    Validated Documents (3)

    Target: CD3E Granzyme B CD8 alpha Cytokeratin Ki-67 SOX10

    Reactivity: Human

    Platforms: PhenoImager™ HT

    Detection of human CD3E (cyan), CD8 alpha (red), cytokeratin (yellow), granzyme B (green), Ki-67 (orange) and SOX10 (magenta) in FFPE breast carcinoma 1 Figure
    $2,086.00
  • NEW!
    Tumor Infiltrating Lymphocyte (TIL) PathPlex® Panel (CD3E, CD8 alpha, CD20)

    Bethyl Laboratories Catalog # A810-002

    bethyl
    Validated Documents (3)

    Target: CD3E CD8 alpha CD20

    Reactivity: Human

    Platforms: PhenoImager™ HT

    Detection of human CD3E (yellow), CD8 alpha (red), and CD20 (green) in FFPE tonsil by IHC-IF. 1 Figure
    $1,043.00
  • NEW!
    Activated T Cell PathPlex® Panel (CD3E, Cytokeratin, CD8 alpha, CD68, Ki-67, PD-L1)

    Bethyl Laboratories Catalog # A810-005

    bethyl
    Validated Documents (3)

    Target: CD3E Cytokeratin CD8 alpha CD68 Ki-67 PD-L1

    Reactivity: Human

    Platforms: PhenoImager™ HT

    Detection of human CD3E (cyan), CD8 alpha (green), CD68 (orange), CK (red), Ki67 (yellow) and PD-L1 (white) in FFPE HNSCC by IHC-IF. 1 Figure
    $2,086.00
  • NEW!
    Immune Localization PathPlex® Panel (CD3E, CD68, CD20)

    Bethyl Laboratories Catalog # A810-003

    bethyl
    Validated Documents (3)

    Target: CD3E CD68 CD20

    Reactivity: Human

    Platforms: PhenoImager™ HT

    Detection of human CD3E (yellow), CD68 (red), and CD20 (green) in FFPE lung carcinoma by IHC-IF. 1 Figure
    $1,043.00
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