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Rabbit anti-ADE2 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
ADE2
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to ADE2 immobilized on solid support.

The epitope recognized by A304-546A maps to a region between residue 1 to 50 of human Phosphoribosylaminoimidazole Carboxylase using the numbering given in entry NP_001072992.1 (GeneID 10606).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to ADE2 immobilized on solid support.

The epitope recognized by A304-546A-T maps to a region between residue 1 to 50 of human Phosphoribosylaminoimidazole Carboxylase using the numbering given in entry NP_001072992.1 (GeneID 10606).
Country of Origin
USA

Additional Product Information

ADE2 is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis [taken from NCBI Entrez Gene (Gene ID: 10606)].

10606
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
P22234
Multifunctional protein ADE2

Alternate Names

ADE2; ADE2H1; AIR carboxylase; AIRC; multifunctional protein ADE2; multifunctional protein ADE2H1; PAIS; phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; phosphoribosylaminoimidazolesuccinocarboxamide synthase; SAICAR synthetase

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.