Rabbit anti-AKT1 Recombinant Monoclonal Antibody [BLR245L]
Catalog #
AKT1
Human
,Mouse
Flow Cyt
,WB
Rabbit
Recombinant Monoclonal
BLR245L
Whole IgG
Between 100 and 150
IgG
Unconjugated
Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 100 and 150 of human RAC-alpha serine/threonine-protein kinase (aka AKT1) using the numbering given in entry NP_001369359.1 (Gene ID 207).
USA
AKT1 is a serine-threonine kinase that functions downstream of PI-3 kinase and is known to phosphorylate several proteins. AKT1 mediates the effects of several growth factors such as insulin, IGF-1, EGF, and PDGF to control cell survival and apoptosis. There are numerous substrates of AKT1, some of which are: GSK3-alpha and beta, mTOR, TSC2, Bad, c-Raf, and caspase 9.
Alternate Names
AKT; AKT1m; CWS6; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein kinase B; protein kinase B alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; serine-threonine protein kinase; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
Applications