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Rabbit anti-ALDH18A1/P5CS Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
ALDH18A1/P5CS
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 745 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to ALDH18A1/P5CS immobilized on solid support.

The epitope recognized by A304-803A maps to a region between residue 745 to 795 of human Aldehyde Dehydrogenase 18 Family, Member A1 using the numbering given in entry P54886.2 (GeneID 5832).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to ALDH18A1/P5CS immobilized on solid support.

The epitope recognized by A304-803A-T maps to a region between residue 745 to 795 of human Aldehyde Dehydrogenase 18 Family, Member A1 using the numbering given in entry P54886.2 (GeneID 5832).
Country of Origin
USA

Additional Product Information

ALDH18A1/P5CS is a bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P54886].

5832
ALDH18A1
aldehyde dehydrogenase 18 family member A1
P54886
Delta-1-pyrroline-5-carboxylate synthase

Alternate Names

ADCL3; aldehyde dehydrogenase family 18 member A1; ARCL3A; delta1-pyrroline-5-carboxlate synthetase; delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthetase; Gamma-glutamyl kinase; Gamma-glutamyl phosphate reductase (GPR); Glutamate 5-kinase (GK); Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; GSAS; P5CS; PYCS; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase); spastic paraplegia 9 (autosomal dominant); Spastic paraplegia-9 (spastic paraparesis with amyotrophy, cataracts and gastroesophageal reflux); SPG9; SPG9A; SPG9B

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.