Rabbit anti-ASC2 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00019 maps to a region between residue 2000 and the C-terminus (residue 2063) of human Activating Signal Cointegrator-2 using the numbering given in Swiss-Prot entry Q14686 (GeneID 23054). Antibody was affinity purified using an epitope specific to ASC2 immobilized on solid support.
The epitope recognized by IHC-00019-T maps to a region between residue 2000 and the C-terminus (residue 2063) of human Activating Signal Cointegrator-2 using the numbering given in Swiss-Prot entry Q14686 (GeneID 23054).
Additional Product Information
Activating signal co-integrator 2 (ASC2) functions as a hormone-dependent transcriptional coactivator in cooperation with nuclear receptors such as steroids, retinoids, thyroid hormone, vitamin D3 and prostanoids. ASC2 also interacts with basal transcription factors and may also influence gene expression through its association with histone modifiers. ASC2 has been identified as an amplified gene in breast and other human cancers.
Alternate Names
Activating signal cointegrator 2; activating signal cointegrator-2; AIB3; amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ASC2; ASC-2; cancer-amplified transcriptional coactivator ASC-2; NRC; NRC RAP250; nuclear receptor coactivator 6; nuclear receptor coactivator RAP250; nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; Peroxisome proliferator-activated receptor-interacting protein; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; Thyroid hormone receptor-binding protein; TRBP
Applications
Epitope exposure is recommended.