Rabbit anti-ASCC1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-871A maps to a region between residue 1 and 50 of human Activating Signal Cointegrator 1 Complex Subunit 1 using the numbering given in entry NP_001185728.1 (GeneID 51008).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to ASCC1 immobilized on solid support.
The epitope recognized by A303-871A-T maps to a region between residue 1 and 50 of human Activating Signal Cointegrator 1 Complex Subunit 1 using the numbering given in entry NP_001185728.1 (GeneID 51008).
Additional Product Information
Activating signal cointegrator 1 complex subunit 1 (ASCC1) is a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). ASCC1 contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in the ASCC1 gene are associated with Barrett esophagus and esophageal adenocarcinoma [taken from NCBI Entrez Gene (Gene ID: 51008)].
Alternate Names
activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit P50; ASC1p50; CGI-18; p50; SMABF2; trip4 complex subunit p50
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).