Rabbit anti-BAP1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-242A-T maps to a region between residue 500 and 550 of human BRCA1-associated protein 1 using the numbering given in entry NP_004647.1 (GeneID 8314).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to BAP1 immobilized on solid support.
The epitope recognized by A302-242A maps to a region between residue 500 and 550 of human BRCA1-associated protein 1 using the numbering given in entry NP_004647.1 (GeneID 8314).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
BRCA1-associated protein 1 (BAP1) functions as a C-terminal ubiquitin hydrolase and may be involved in the transduction of signals in the BRCA1 pathway. BAP1 is also implicated to be a tumor suppressor as defects in BAP1 are found in non-small cell lung cancer cell lines.
Alternate Names
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; cerebral protein 6; cerebral protein-13; HUCEP-13; hucep-6; ubiquitin carboxyl-terminal hydrolase BAP1; UCHL2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.