Rabbit anti-Bcl11b Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-383A maps to a region between residues 1 and 50 of human B-cell CLL/lymphoma 11B using the numbering given in entry NP_612808.1 (GeneID 64919).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Bcl11b immobilized on solid support.
The epitope recognized by A300-383A-T maps to a region between residues 1 and 50 of human B-cell CLL/lymphoma 11B using the numbering given in entry NP_612808.1 (GeneID 64919).
Additional Product Information
Bcl11b is a zinc-finger transcription factor that is homologous to the proto-oncogene Bcl11a. Bcl11b functions in T-cell development, and as a tumor suppressor, plays a role in T-cell lymphoma pathogenesis. Bcl11b interacts with ARP1, SIRT1, and TFCOUP1 to modulate transcription.
Alternate Names
ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BCL-11B; BCL11B/TRDC fusion; COUP-TF-interacting protein 2; CTIP2; CTIP-2; hRit1; hRIT1-alpha; IDDFSTA; IMD49; radiation-induced tumor suppressor gene 1 protein; RIT1; zinc finger protein hRit1 alpha; ZNF856B
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.