Rabbit anti-c-Maf Antibody Affinity Purified
Product Details
Specifications
Antibody was affinity purified using the peptide immobilized on solid support.
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using the peptide immobilized on solid support.
The epitope recognized by A300-613A-T maps to a region between residue 150 and 200 of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog (c-Maf) using the numbering given in entry NP_001020748.2 (GeneID 17132).
Additional Product Information
c-Maf is part of the Maf family of transcription factors that possess a conserved basic region and a leucine zipper domain that mediate DNA and protein-protein binding and plays an important role in tissue-specific gene regulation and cell differentiation. c-Maf is a transcriptional activator of interleukin 4 and 10 in T-cells, and is involved in lens fiber cell differentiation. c-Maf translocation has been observed in human multiple myeloma and may be oncogenic.
Alternate Names
2810401A20Rik; A230108G15Rik; avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog; AW047063; c-maf; c-Maf long form; proto-oncogene c-maf; transcription factor Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).