Rabbit anti-CC2D1A Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-285A maps to a region between residues 1 and 50 of human Coiled-coil and C2 Domain Containing 1A using the numbering given in TrEMBL entry Q6P1N0 (GeneID 54862).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to CC2D1A immobilized on solid support.
The epitope recognized by A300-285A-T maps to a region between residues 1 and 50 of human Coiled-coil and C2 Domain Containing 1A using the numbering given in TrEMBL entry Q6P1N0 (GeneID 54862).
Additional Product Information
CC2D1A functions as a transcriptional repressor of FRE (five repressor element) DNA element. As a repressor of this element, CC2D1A represses serotonin-1A receptor and dopamine-D2 receptor gene expression and has been linked to nonsyndromic mental retardation and psychiatric illnesses. The DNA binding and repressor activities of CC2D1A are regulated by the calcium-calmodulin-dependent protein kinase.
Alternate Names
Akt kinase-interacting protein 1; coiled-coil and C2 domain-containing protein 1A; five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; FRE under dual repression-binding protein 1; FREUD-1; Freud-1/Aki1; MRT3; putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.