Rabbit anti-CELSR1 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions.CELSR1 is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis [taken from NCBI Entrez Gene (Gene ID: 9620)].
Alternate Names
ADGRC1; adhesion G protein-coupled receptor C1; cadherin EGF LAG seven-pass G-type receptor 1; cadherin family member 9; cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); CDHF9; flamingo homolog 2; FMI2; HFMI2; ME2; protocadherin flamingo 2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.