Rabbit anti-CENP-J Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-986A maps to a region between residue 675 and 725 of human Centromere Protein J using the numbering given in entry NP_060921.2 (GeneID 55835).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to CENP-J immobilized on solid support.
The epitope recognized by A302-986A-T maps to a region between residue 675 and 725 of human Centromere Protein J using the numbering given in entry NP_060921.2 (GeneID 55835).
Additional Product Information
CENP-J is a centromeric protein that has been reported to play a role in mitosis and transcription. CENP-J plays a role in normal spindle morphology, transcription, cell signaling, and lysosomal trafficking. CENP-J is reported to be an inhibitor of microtubule assembly and may function to regulate microtubule dynamics at the centrosomes. In transcription, CENP-J functions as a coactivator in Stat5- and NF-kappaB-mediated transcription. Mutations in CENP-J are associated with autosomal recessive microcephaly.
Alternate Names
BM032; CENP-J; centromere protein J; centrosomal P4.1-associated protein; CPAP; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; Sas-4; SASS4; SCKL4
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).