Rabbit anti-CTF18 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00373 maps to a region between residue 25 and 75 of human chromosome transmission fidelity factor 18 using the numbering given in entry NP_071375.1 (GeneID 63922).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to CTF18 immobilized on solid support.
The epitope recognized by IHC-00373-T maps to a region between residue 25 and 75 of human chromosome transmission fidelity factor 18 using the numbering given in entry NP_071375.1 (GeneID 63922).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
CTF18 (Chromosome Transmission Fidelity protein 18 homolog) is part of the CTF18-RFC (Replication Factor C) complex composed of CTF18, CTF8, DCC1, and four RFC subunits. This complex has been shown to be important for the establishment of sister chromatid cohesion and functions as a proliferating cell nuclear antigen (PCNA) loader for DNA synthesis.
Alternate Names
C16orf41; C321D2.2; C321D2.3; C321D2.3 (novel protein); C321D2.4; C321D2.4 (novel protein); CHL12; chromosome transmission fidelity protein 18 homolog; Ctf18; CTF18, chromosome transmission fidelity factor 18 homolog; hCTF18; homolog of yeast CHL12; RUVBL; some homology with holliday junction DNA helicase RUVB like
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.