Rabbit anti-Cul2 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00692-T maps to a region between residue 150 and 200 of human cullin 2 using the numbering given in entry NP_003582.2 (GeneID 8453).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Cul2 immobilized on solid support.
The epitope recognized by IHC-00692 maps to a region between residue 150 and 200 of human cullin 2 using the numbering given in entry NP_003582.2 (GeneID 8453).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Cullin-2 (Cul2) is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. Cul2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13617].
Alternate Names
CUL-2; cullin-2; testis secretory sperm-binding protein Li 238E
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.