Rabbit anti-Cul4a IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00145 maps to a region between residues 700 and the C-terminus (residue 759) of human Cullin 4A using the numbering given in entry NP_001008895.1 (GeneID 8451). Antibody was affinity purified using an epitope specific to Cul4a immobilized on solid support.
The epitope recognized by IHC-00145-T maps to a region between residues 700 and the C-terminus (residue 759) of human Cullin 4A using the numbering given in entry NP_001008895.1 (GeneID 8451).
Additional Product Information
Cul4a is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Several Cul4 E3 ligase complexes have been identified as important in cell cycle regulation and the DNA damage checkpoint response.
Alternate Names
CUL-4A; cullin-4A
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.