Rabbit anti-DOCK11 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP allows an exchange for GTP and subsequent downstream signaling by the GTPase.
Alternate Names
ACG; Activated Cdc42-associated guanine nucleotide exchange factor; Activated Cdc42-associated guanine nucleotide exchange factor, ACG; bB128O4.1; bB128O4.1.1 (novel protein); dedicator of cytokinesis protein 11; ZIZ2; zizimin2; zizimin-2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.