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Primary Antibodies

Rabbit anti-DYNC1LI1 Antibody Affinity Purified

Name: Rabbit anti-DYNC1LI1 Antibody
Brand: Bethyl Laboratories
SKU: A304-209A
Price: 131 USD

Bethyl Laboratories Catalog #

Target:

DYNC1LI1

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 400 and 450

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00

Qty:

Product Details

Specifications

Verified Reactivity

Human

Presumed Reactivity

Mouse, Rat

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures

Antibody was affinity purified using an epitope specific to DYNC1LI1 immobilized on solid support.

The epitope recognized by A304-209A-T maps to a region between residue 400 to 450 of human Dynein, Cytoplasmic 1, Light Intermediate Chain 1 using the numbering given in entry NP_057225.2 (GeneID 51143).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to DYNC1LI1 immobilized on solid support.

The epitope recognized by A304-209A maps to a region between residue 400 to 450 of human Dynein, Cytoplasmic 1, Light Intermediate Chain 1 using the numbering given in entry NP_057225.2 (GeneID 51143).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Country of Origin

USA

Additional Product Information

Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. It may play a role in binding dynein to membranous organelles or chromosomes and is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 Is required for progress through the spindle assembly checkpoint [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6G9].

Gene ID: 51143

Gene Symbol: DYNC1LI1

Gene Name: dynein cytoplasmic 1 light intermediate chain 1

Uniprot ID: Q9Y6G9

Protein Name: Cytoplasmic dynein 1 light intermediate chain 1

Alternate Names

cytoplasmic dynein 1 light intermediate chain 1; DLC-A; DNCLI1; dynein light chain A; dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 1; LIC1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.