Rabbit anti-FANCA Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-980A maps to a region between residue 1405 and 1455 of human Fanconi anemia, complementation group A using the numbering given in entry NP_000126.2 (GeneID 2175).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to FANCA immobilized on solid support.
The epitope recognized by A301-980A-T maps to a region between residue 1405 and 1455 of human Fanconi anemia, complementation group A using the numbering given in entry NP_000126.2 (GeneID 2175).
Additional Product Information
FANCA (Fanconi anemia, complementation group A) is a protein involved in DNA repair. Defects in FANCA are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCA gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.
Alternate Names
FA; FA1; FAA; FACA; FAH; FA-H; FANCH; Fanconi anemia complementation group A; Fanconi anemia group A protein; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.