Rabbit anti-FANCM Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-637A maps to a region between residue 1 to 50 of human Fanconi anemia, complementation group M using the numbering given in entry NP_065988.1 (GeneID 57697 ).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to FANCM immobilized on solid support.
The epitope recognized by A302-637A-T maps to a region between residue 1 to 50 of human Fanconi anemia, complementation group M using the numbering given in entry NP_065988.1 (GeneID 57697 ).
Additional Product Information
FANCM (Fanconi anemia, complementation group M) is a protein involved in DNA repair. Defects in FANCM are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCM gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.
Alternate Names
ATP-dependent RNA helicase FANCM; FAAP250; Fanconi anemia complementation group M; Fanconi anemia group M protein; fanconi anemia-associated polypeptide of 250 kDa; KIAA1596; POF15; Protein FACM; protein Hef ortholog; SPGF28
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.