Rabbit anti-Filamin A Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-133A maps to a region between residue 400 and 450 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Filamin A immobilized on solid support.
The epitope recognized by A301-133A-T maps to a region between residue 400 and 450 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Additional Product Information
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.
Alternate Names
ABP-280; ABPX; actin binding protein 280; Actin-binding protein 280; alpha-filamin; CSBS; CVD1; endothelial actin-binding protein; epididymis secretory sperm binding protein; FGS2; filamin A, alpha; filamin-1; filamin-A; FLN; FLN1; FLN-A; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).