Rabbit anti-FUS Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.
Alternate Names
75 kDa DNA-pairing protein; ALS6; ETM4; FUS/ERG chimeric protein; FUS/ERG fusion protein; FUS1; fused in sarcoma; fusion gene in myxoid liposarcoma; fus-like protein; heterogeneous nuclear ribonucleoprotein P2; HNRNPP2; oncogene FUS; oncogene TLS; POMP75; RNA-binding protein FUS; TLS; translocated in liposarcoma protein
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.