Rabbit anti-GAB1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-288A maps to a region between residue 644 and 694 of human GRB2-Associated Binding Protein 1 using the numbering given in entry NP_002030.2 (GeneID 2549).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to GAB1 immobilized on solid support.
The epitope recognized by A303-288A-T maps to a region between residue 644 and 694 of human GRB2-Associated Binding Protein 1 using the numbering given in entry NP_002030.2 (GeneID 2549).
Additional Product Information
GRB2-associated-binding protein 1 (GAB1) is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis [taken from NCBI Entrez Gene (Gene ID: 2549)].
Alternate Names
DFNB26; GRB2-associated binder 1; GRB2-associated-binding protein 1; growth factor receptor bound protein 2-associated protein 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.