Rabbit anti-HMG2a IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00173 maps to a region between residues 125 and 175 of human High-Mobility Group 2A using the numbering given in entry NP_005333.2 (GeneID 3149). Antibody was affinity purified using an epitope specific to HMG2a immobilized on solid support.
The epitope recognized by IHC-00173-T maps to a region between residues 125 and 175 of human High-Mobility Group 2A using the numbering given in entry NP_005333.2 (GeneID 3149).
Additional Product Information
High mobility group protein 2a (HMG2a) is a member of the Hmg-box subfamily of proteins that possesses a DNA-binding HmG-box domain. The HMG2a gene is X-linked and its expression is localized to the bone marrow and is a marker for hematopoietic stem cells (HSCs). HMG2a plays a role in cell-fate decisions of HSCs and functions by altering DNA structure to facilitate transcription factor binding.
Alternate Names
high mobility group protein 2a; High mobility group protein 4; high mobility group protein B3; high-mobility group (nonhistone chromosomal) protein 4; HMG2A; HMG-2a; HMG4; HMG-4
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.