Rabbit anti-JAZ Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A304-341A maps to a region between residue 244 to 294 of human Just Another Zinc Finger Protein using the numbering given in entry NP_036411.1 (GeneID 23567).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to JAZ immobilized on solid support.
The epitope recognized by A304-341A-T maps to a region between residue 244 to 294 of human Just Another Zinc Finger Protein using the numbering given in entry NP_036411.1 (GeneID 23567).
Additional Product Information
JAZ (just another zinc finger protein) is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. JAZ may be involved in cell growth and survival [taken from NCBI Entrez Gene (Gene ID: 23567)].
Alternate Names
double-stranded RNA-binding zinc finger protein JA; ZJA; Zjust another zinc finger protein; Zfp346; zinc finger protein 346
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.