Rabbit anti-LAP1B IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00537 maps to a region between residue 275 and 325 of human lamina associated polypeptide 1B using the numbering given in entry NP_056417.2 (GeneID 26092).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to LAP1B immobilized on solid support.
The epitope recognized by IHC-00537-T maps to a region between residue 275 and 325 of human lamina associated polypeptide 1B using the numbering given in entry NP_056417.2 (GeneID 26092).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.
Alternate Names
lamina-associated polypeptide 1B; lamin-associated protein 1B; LAP1; LAP1B; LGMD2Y; torsin A interacting protein 1; torsin-1A-interacting protein 1
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.