Rabbit anti-MAML3 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00447 maps to a region between residue 1100 and the C-terminus (residue 1133) human Mastermind-Like 3 using the numbering given in entry NP_061187.2 (GeneID 55534).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to MAML3 immobilized on solid support.
The epitope recognized by IHC-00447-T maps to a region between residue 1100 and the C-terminus (residue 1133) human Mastermind-Like 3 using the numbering given in entry NP_061187.2 (GeneID 55534).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML3 is a coactivator for NOTCH signaling. MAML3 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors.
Alternate Names
CAG repeat containing (glia-derived nexin I alpha); CAGH3; ERDA3; expanded repeat domain, CAG/CTG 3; GDN; MAM2; MAM-2; mam-3; mastermind-like protein 3; polyglutamine rich; TNRC3; trinucleotide repeat containing 3
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.