Rabbit anti-Matrin 3 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-590A-T maps to a region between residues 475 and 500 of human Matrin 3 using the numbering given in entry NP_061322.2 (GeneID 9782).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Matrin 3 immobilized on solid support.
The epitope recognized by A300-590A maps to a region between residues 475 and 500 of human Matrin 3 using the numbering given in entry NP_061322.2 (GeneID 9782).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Matrin 3 is a nuclear matrix protein that has been observed to mediate multiple cellular processes. Matrin 3 can function to withhold defective RNAs within the nucleus by anchoring them to the nuclear matrix and modulate the promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). Matrin 3 has also been demonstrated to be the main PKA substrate following NMDA receptor activation in NMDA-induced neuronal cell death.
Alternate Names
ALS21; matrin-3; MPD2; VCPDM; vocal cord and pharyngeal weakness with distal myopathY
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.