Rabbit anti-NCOA2/SRC2 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Nuclear Receptor Coactivator 2 (NCOA2) is a member of the p160 family of nuclear receptor coactivators that also includes steroid receptor coactivator-1 (SRC-1) and p300/CBP-interacting protein (p/CIP). As Coactivators, this group of proteins helps recruit acetyltransferases and methyltransferases such as p300/CBP and CARM1 to facilitate chromatin remodeling and transcription factor recruitment, and to enhance gene expression. NCOA2 has been demonstrated to be important for the control of energy balance between white and brown adipose tissue.
Alternate Names
bHLHe75; class E basic helix-loop-helix protein 75; glucocorticoid receptor-interacting protein-1; GRIP1; hTIF2; KAT13C; NCoA-2; nuclear receptor coactivator 2; p160 steroid receptor coactivator 2; SRC2; TIF2; transcriptional intermediary factor 2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.