Rabbit anti-NRIP IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00735 maps to a region between residue 600 and 650 of human nuclear receptor interaction protein (IQ motif and WD repeats 1) using the numbering given in entry NP_001017977.1 (GeneID 55827).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to NRIP immobilized on solid support.
The epitope recognized by IHC-00735-T maps to a region between residue 600 and 650 of human nuclear receptor interaction protein (IQ motif and WD repeats 1) using the numbering given in entry NP_001017977.1 (GeneID 55827).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Nuclear receptor interaction protein (NRIP) was isolated as a ligand-dependent coactivator of the androgen receptor (AR) and glucocorticoid receptor (GR). NRIP was found to enhance the promoter activity of the AR-driven PSA promoter. NRIP is a target gene for AR and Sp1, and complex formation between AR and NRIP protects AR protein from proteasome degradation.
Alternate Names
1200006M05Rik; androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; IQWD1; MSTP055; NRIP; nuclear receptor interaction protein; PC326
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.