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Primary Antibodies

Rabbit anti-OBFC2A Antibody Affinity Purified

Name: Rabbit anti-OBFC2A Antibody
Brand: Bethyl Laboratories
SKU: A302-254A
Price: 131 USD

Bethyl Laboratories Catalog #

Target:

OBFC2A

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00

Qty:

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures

Antibody was affinity purified using an epitope specific to OBFC2A immobilized on solid support.

The epitope recognized by A302-254A-T maps to a region between residue 1 to 50 of human oligonucleotide/oligosaccharide-binding fold containing 2A using the numbering given in entry NP_001026886.1 (GeneID 64859).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to OBFC2A immobilized on solid support.

The epitope recognized by A302-254A maps to a region between residue 1 to 50 of human oligonucleotide/oligosaccharide-binding fold containing 2A using the numbering given in entry NP_001026886.1 (GeneID 64859).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Country of Origin

USA

Additional Product Information

OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.

Gene ID: 64859

Gene Symbol: NABP1

Gene Name: nucleic acid binding protein 1

Uniprot ID: Q96AH0

Protein Name: SOSS complex subunit B2

Alternate Names

hSSB2; Nucleic acid-binding protein 1; OBFC2A; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2; SSB2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.