Rabbit anti-Pds5B IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00381 maps to a region between residues 1200 and 1250 of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Pds5B immobilized on solid support.
The epitope recognized by IHC-00381-T maps to a region between residues 1200 and 1250 of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Pds5B is a cohesin interacting protein. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensures proper segregation of chromosomes. Pds5B may play a specific role in the stabilization and destabilization of cohesin-mediated cohesion. Pds5B expression has been demonstrated to be androgen-induced and mediate the androgen-induced proliferative arrest of human prostate cells.
Alternate Names
androgen induced inhibitor of proliferation; androgen-induced proliferation inhibitor; androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; APRIN; AS3; CG008; sister chromatid cohesion protein PDS5 homolog B
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.