Rabbit anti-Phospho Aurora A (T288) IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00067 maps to a region surrounding residue 288 when Threonine 288 is phosphorylated of human Aurora A Kinase using the numbering given entry NP_003591.2 (GeneID 6790). Antibody was affinity purified using an epitope specific to Phospho Aurora A (T288) immobilized on solid support.
The epitope recognized by IHC-00067-T maps to a region surrounding residue 288 when Threonine 288 is phosphorylated of human Aurora A Kinase using the numbering given entry NP_003591.2 (GeneID 6790).
Additional Product Information
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers.
Alternate Names
AIK; ARK1; ARK-1; AURA; aurora 2; aurora kinase A; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; Aurora-related kinase 1; breast tumor-amplified kinase; BTAK; hARK1; PPP1R47; protein phosphatase 1, regulatory subunit 47; serine/threonine protein kinase 15; Serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A; STK15; STK6; STK7
Applications
Formaldehyde-Fixed Cells 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.