Rabbit anti-PLK1 IHC Antibody Affinity Purified
Product Details
Specifications
The epitopes recognized by IHC-00071 maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347). Antibody was affinity purified using an epitope specific to PLK1 immobilized on solid support.
The epitope recognized by IHC-00071-T maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).
Additional Product Information
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis.
Alternate Names
cell cycle regulated protein kinase; PLK; PLK-1; polo (Drosophia)-like kinase; Polo-like kinase 1; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13
Applications
Formaldehyde-Fixed Cells 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.