Rabbit anti-PLRG1 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00404 maps to a region between residue 464 and 514 of human pleiotropic regulator 1 using the numbering given in entry NP_002660.1 (GeneID 5356).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to PLRG1 immobilized on solid support.
The epitope recognized by IHC-00404-T maps to a region between residue 464 and 514 of human pleiotropic regulator 1 using the numbering given in entry NP_002660.1 (GeneID 5356).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Pleiotropic regulator 1 (PLRG1) has been shown to be a part of sub-spliceosomal protein complexes. It is highly conserved across species and is essential for pre-mRNA splicing. PLRG1 interacts with human CDC5. This interaction has also been shown to be essential to pre-mRNA splicing.
Alternate Names
Cwc1; pleiotropic regulator 1; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); PRL1; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homolog
Applications
Epitope exposure is recommended.
Epitope exposure with citrate or tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.