Rabbit anti-Rad21 Recombinant Monoclonal Antibody [BLR052F]
Catalog #
Rad21
Human
,Mouse
Flow Cyt
,WB
Rabbit
Recombinant Monoclonal
BLR052F
Whole IgG
Between 581 and C-terminus
IgG
Unconjugated
Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 581 and the C-terminus (residue 631) of human Double-strand-break repair protein Rad21 homolog using the numbering given in entry NP_006256.1 (Gene ID 5885).
Rad21, also called SCC1 (sister chromatid cohesion protein 1), is part of the mitotic cohesin complex that consist of SMC1, SMC3, SCC3 and SCC1. The cohesin complex is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination. Rad21 has been demonstrated to be cleaved by caspase proteins to trigger sister chromatid separation and during apoptotic signaling.
Alternate Names
CDLS4; double-strand-break repair protein rad21 homolog; hHR21; HR21; HRAD21; kleisin; MCD1; MGS; nuclear matrix protein 1; NXP1; NXP-1; protein involved in DNA double-strand break repair; RAD21 homolog; SCC1; SCC1 homolog; sister chromatid cohesion 1
Applications