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Rabbit anti-Rad50 IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
Rad50
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 700 and 750
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

$131.00 $492.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Presumed Reactivity
Dog, Rabbit, Bovine, Monkey
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to Rad50 immobilized on solid support.

The epitope recognized by IHC-00076 maps to a region between residue 700 and 750 of human Rad50 using the numbering given in entry NP_005723.2 (GeneID 10111).
Antibody was affinity purified using an epitope specific to Rad50 immobilized on solid support.

The epitope recognized by IHC-00076-T maps to a region between residue 700 and 750 of human Rad50 using the numbering given in entry NP_005723.2 (GeneID 10111).
Country of Origin
USA

Additional Product Information

Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.

10111
RAD50
RAD50 double strand break repair protein
Q92878
DNA repair protein RAD50

Alternate Names

DNA repair protein RAD50; hRad50; NBSLD; RAD50 homolog, double strand break repair protein; RAD502

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.