NEW!

Primary Antibodies

Rabbit anti-RanGAP1 Antibody Affinity Purified

Name: Rabbit anti-RanGAP1 Antibody
Brand: Bethyl Laboratories
SKU: A302-027A
Price: 121 USD

Bethyl Laboratories Catalog #

Citations (1)

Target:

RanGAP1

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 400 and 450

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$121.00 $433.00

Qty:

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Request Formulation Change

Country of Origin

USA

Additional Product Information

The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.

Gene ID: 5905

Gene Symbol: RANGAP1

Gene Name: Ran GTPase activating protein 1

Uniprot ID: P46060

Protein Name: Ran GTPase-activating protein 1

Alternate Names

Fug1; ran GTPase-activating protein 1; RANGAP; RanGAP1; SD; segregation distorter homolog; segregation distortion

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.