Rabbit anti-SAMHD1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-690A maps to a region between residue 450 and 500 of human SAM Domain and HD Domain 1 using the numbering given in entry NP_056289.2 (GeneID 25939).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to SAMHD1 immobilized on solid support.
The epitope recognized by A303-690A-T maps to a region between residue 450 and 500 of human SAM Domain and HD Domain 1 using the numbering given in entry NP_056289.2 (GeneID 25939).
Additional Product Information
SAM domain and HD domain-containing protein 1 (SAMHD1) is a putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. SAMHD1 may play a role in mediating proinflammatory responses to TNF-alpha signaling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y3Z3].
Alternate Names
CHBL2; DCIP; dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; HDDC1; hSAMHD1; monocyte protein 5; MOP-5; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; SBBI88
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.