Rabbit anti-SRcyp IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00547 maps to a region between residue 450 and 500 of human SR-cyclophilin (Peptidyl-prolyl isomerase G) using the numbering given in entry NP_004783.2 (GeneID 9360).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to SRcyp immobilized on solid support.
The epitope recognized by IHC-00547-T maps to a region between residue 450 and 500 of human SR-cyclophilin (Peptidyl-prolyl isomerase G) using the numbering given in entry NP_004783.2 (GeneID 9360).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing.
Alternate Names
CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; cyclophilin G; CYP; peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); PPIase G; rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.