Rabbit anti-TPP1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-069A maps to a region between residue 150 and 200 of human Adrenocortical Dysplasia Homolog using the numbering given in entry NP_001075955.1 (GeneID 65057).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to TPP1 immobilized on solid support.
The epitope recognized by A303-069A-T maps to a region between residue 150 and 200 of human Adrenocortical Dysplasia Homolog using the numbering given in entry NP_001075955.1 (GeneID 65057).
Additional Product Information
TPP1 is involved in telomere function and is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, TPP1 plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere [taken from NCBI Entrez Gene (Gene ID: 65057].
Alternate Names
adrenocortical dysplasia homolog; adrenocortical dysplasia protein homolog; PIP1; POT1 and TIN2-interacting protein; PTOP; TIN2 interacting protein 1; TINT1; TPP1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.