Rabbit anti-Treslin Antibody Affinity Purified
Catalog #
Treslin
Human
WB
Rabbit
Polyclonal
Whole IgG
Between 1000 and 1050
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z2Z1].
Alternate Names
C15orf42; SLD3; topBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; TopBP1-interacting, replication-stimulating protein; Treslin
Applications