Rabbit anti-TRIP1/SUG1 Antibody, Affinity Purified
Product Details
Specifications
The epitope recognized by A300-791A-T maps to a region between residue 1 and 50 of human Thyroid Receptor Interactor 1 using the numbering given in entry NP_002796.4 (GeneID 5705). Antibody was affinity purified using an epitope specific to TRIP1/SUG1 immobilized on solid support.
The epitope recognized by A300-791A maps to a region between residue 1 and 50 of human Thyroid Receptor Interactor 1 using the numbering given in entry NP_002796.4 (GeneID 5705).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Thyroid receptor interacting protein 1 (TRIP1) was originally identified as a protein that interacts with the thyroid receptor and is homologous to the yeast SUG1 protein, a transcriptional coactivator. It was later identified as an ATPase subunit of the 26S proteasome, a multicatalytic proteinase complex, and has also been shown to associate with nuclear receptors and transcription factors. TRIP1/SUG1 may function to regulate transcription factor abundance by targeting them for proteasome degradation.
Alternate Names
26S protease regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; 26S proteasome regulatory subunit 8; MSUG1 protein; p45; p45/SUG; proteasome (prosome, macropain) 26S subunit, ATPase, 5; proteasome 26S ATPase subunit 5; Proteasome 26S subunit ATPase 5; proteasome subunit p45; S8; SUG1; SUG-1; Tat-binding protein homolog 10; TBP10; testicular tissue protein Li 149; thyroid hormone receptor-interacting protein 1; thyroid receptor interactor 1; TRIP1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).