Rabbit anti-VCP IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00084 maps to a region between residue 750 and the C-terminus (residue 806) of human Valosin-Containing Protein using the numbering given in entry NP_009057.1 (GeneID 7415). Antibody was affinity purified using an epitope specific to VCP immobilized on solid support.
The epitope recognized by IHC-00084-T maps to a region between residue 750 and the C-terminus (residue 806) of human Valosin-Containing Protein using the numbering given in entry NP_009057.1 (GeneID 7415).
Additional Product Information
Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis.
Alternate Names
15S Mg(2+)-ATPase p97 subunit; CDC48; p97; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; Valosin-containing protein; VCP
Applications
Epitope exposure is recommended.