Rabbit anti-WDR5 IHC Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
WD-repeat domain 5 (WDR5) is a member of the WD repeat family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WDR5 contains 7 WD repeats and is a core subunit of the human MLL and SET1 histone H3 lys4 methyltransferase complexes. WDR5 functions in facilitating the assembly of MLL and SET1 chromatin-modifiying complexes.
Alternate Names
BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.