Rabbit anti-XRN2 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-103A maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to XRN2 immobilized on solid support.
The epitope recognized by A301-103A-T maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Additional Product Information
XRN2 is a 5’-to-3’ exoribonuclease involved in 3’-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3’-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3’-end processing machinery by p54nrb/PSF.
Alternate Names
5'-3' exoribonuclease 2; Dhm1-like protein; DHP protein
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.