Rabbit anti-ZFP106 IHC Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Zinc finger protein homolog 106 (ZFP106) is a C2H2-type zinc finger protein that also contains 2 WD repeats. ZFP106 is highly expressed in striated muscle, brown fat, and developing brain and is regulated by myogenin and nuclear respiratory factor-1 (NRF-1). ZFP106 localizes to the nucleus in association with nucleolar transcriptional machinery. The WD40 repeat in ZFP106 appears to facilitate targeting of ZFP106 to the nucleolus and to mediate the interaction between ZFP106 and testis-specific gene 118 (TSF118). A two-hybrid screen has identified testis-specific Y-encoded-like protein (TSPYL) as a ZFP106 interacting protein. These data suggest an important role for ZFP106 in testis development.
Alternate Names
SH3BP3; SH3-domain binding protein 3; ZFP106; Zfp-106; zinc finger protein 106; zinc finger protein 474; ZNF474
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer pH6.0 will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.