Rabbit anti-ZFP91 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-245A maps to a region between residue 520 and 570 of human Zinc Finger Protein 91 using the numbering given in entry NP_444251.1 (GeneID 80829).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to ZFP91 immobilized on solid support.
The epitope recognized by A303-245A-T maps to a region between residue 520 and 570 of human Zinc Finger Protein 91 using the numbering given in entry NP_444251.1 (GeneID 80829).
Additional Product Information
ZFP91 (zinc finger protein 91 homolog) is an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilization and activation of MAP3K14/NIK. ZFP91 thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. ZFP91 may also play an important role in cell proliferation and/or anti-apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96JP5].
Alternate Names
DMS-8; drug resistance-associated sequence in melanoma 8; DSM-8; E3 ubiquitin-protein ligase ZFP91; FKSG11; penta zinc finger protein; PZF; RING-type E3 ubiquitin transferase ZFP91; ZFP-91; zinc finger protein 757; zinc finger protein 91 homolog; zinc finger protein homologous to Zfp91 in mouse; ZNF757
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.