The AbNano™ VHH discovery platform from Fortis Life Sciences offers comprehensive solutions designed to accelerate your diagnostic and therapeutic development. Whether you need rapid access to off-the-shelf VHH libraries or custom VHH discovery for your specific targets, our fully natural, non-synthetic VHH offerings provide superior diversity and predictable timelines to results.
VHH antibodies have numerous unique properties compared to full-length IgG antibodies including smaller size, monomeric nature, higher stability, ease of production, and rapid development timelines. These benefits make them a powerful tool for a wide range of research, diagnostic, and therapeutic applications.
VHH, also referred to as single-domain antibodies, are antigen-binding fragments derived from the variable heavy domain (VHH) of heavy chain-only antibodies. These antibodies are found in camelids, such as llamas and alpacas.
Single-domain antibodies are 15kDa in molecular weight with dimensions of approximately 2.5nm in diameter and 4nm in height. Single-domain antibodies are ~10 times smaller than conventional antibodies, which are ~150kDa in molecular weight.
We provide VHH antibody discovery services and off-the-shelf VHH discovery libraries. We provide research use only deliverables, but we offer consultation on single-domain antibody sequence selection toward specific diagnostic or therapeutic objectives.
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