Rabbit anti-BHC110/LSD1 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00122 maps to a region between residues 50 and 100 of human FAD-binding protein BRAF35-HDAC complex 110 kDa ( lysine-specific histone demethylase 1) using the numbering given in entry BAA25527.1 (GeneID 23028). Antibody was affinity purified using an epitope specific to BHC110/LSD1 immobilized on solid support.
The epitope recognized by IHC-00122-T maps to a region between residues 50 and 100 of human FAD-binding protein BRAF35-HDAC complex 110 kDa ( lysine-specific histone demethylase 1) using the numbering given in entry BAA25527.1 (GeneID 23028).
Additional Product Information
BHC110/LSD1 is a histone demethylase and a component of several histone deacetylase complexes. BHC110/LSD1 is able to specifically catalyze the demethylation of Lys4 of histone H3. As part of histone deacetylase complexes BHC110/LSD1 functions as a corepressor of transcription. BHC110/LSD1 has also been demonstrated to interact with the androgen receptor and stimulate androgen-receptor-dependent transcription.
Alternate Names
amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; LSD1; lysine (K)-specific demethylase 1A; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.